Meeting notice: The 00.04.18 meeting will be held at 7:30 p.m. at the Royal East (782 Main St., Cambridge), a block down from the corner of Main St. and Mass Ave. If you're new and can't recognize us, ask the manager. He'll probably know where we are. <-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-> Suggested topic: More on the Ecological Immune System. An EIS would control "weeds": replicating entities that threaten to alter the preferred composition of a given ecology. This is a large set that includes GMOs, naturally evolved invading exotics, local species that would work fine somewhere else, only just not right here, and humans bent on environmental despoilation, like poachers or developers making a preemptive strike against endangered species. A satisfactory EIS would be versatile enough to work regardless of trophic level; it would defend members of any kingdom against weeds belonging to any other kingdom. The technology would have two functions: hunting -- sensing -- and killing. Hunting implies pervasive, detailed, and continuous surveillance from autonomous sensor platforms of many types and ranges. These would fly, swim, or be fixed in place as needed. They would be capable of triggering closer looks by other, more sensitive, sensors, where 'closer looks' means altitudes of a few centimeters, sample acquisition, and/or concentrations of a few parts per billion. In a few years we should be able to instrument large numbers of plants and animals for this purpose, which will open up the option of monitoring them as well as their ambient environments. As time goes on the sizes of the hosts that we can recruit in this way will fall and our ability to build genetically engineered 'sentinel species' -- such as trees whose leaves will watch for airborne viruses, pollen, and sphores of interest -- will grow. At first glance this range of tools appears adequate to the function; for instance, viruses could be monitored by analyzing the DNA or RNA injected into arrays of simulated membrane receptors scattered through the environment. This brings us to the next phase. In general, weeds are killed off by spoofing their sensors, which means persuading them to eat poisons instead of prey, seek shelter in traps instead of viable habitats, and/or choose sterile mates; or by introducing a chemical, genetic, or biological agent that recognizes and attacks the weed specifically. These tools should be able to do the job, at least in theory. For instance imagine elephants start dying from a virus. For our purposes it does not matter if this virus is indigenous, a natural exotic, an artifact accidently released to the wild, or a deliberate introduction. Whichever, it would be the job of the EIS to bring it under control. This might be done here by bringing arrays of decoy receptors into the proximity of the threatened elephants. Perhaps the animals could be draped with fibers, each carrying billions of receptors. (Since there are so far as we know no good viruses, only bad and neutral ones, we can build our defenses without worrying about the ecological effect of false positives.) Many variants of this approach can be imagined; one or more seem likely to be effective. The objection can be made that investment required to build the EIS would be considerable. Further, there is not much prospect that this investment will be made, given our failure to resume the manufacture of smallpox vaccine and our passivity at watching invasive exotics rampage through every ecology in the planet. Further, GMOs would probably be necessary for both hunting and killing, and the politics of deliberately releasing GMOs into the wild for any purpose at all are problematical. It seems likely that it will take something unpleasant to end the debate and spur the society in the right direction. Fortunately, such an event looks inevitable. When it arrives the demand for action will be intense and funding will be abundant. It might be smart to prepare a proposal for some aspect of this effort and then wait until the right headlines announce that the moment has come Fred Hapgood <-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-> Announcement Archive: http://www.pobox.com/~fhapgood/nsgpage.html. <-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-><-> If you wish to subscribe to this list (perhaps having received a sample via a forward) send the string 'subscribe nsg' to majordomo@world.std.com. Unsubs follow the same model. Discussion should be sent to nsg-d@world.std.com, which must be subscribed to separately. You must be subscribed to nsg-d to post to it and you must post from the address from which you subscribed (An anti-spam thing). Comments, petitions, and suggestions re list management to: nsg@pobox.com