Meeting notice: 12-15-98; 7:30 p.m. at the Royal East (782 Main St., Cambridge), a block down from the corner of Main St. and Mass Ave. Suggested topic: local autonomy/remote operation While artificial intelligence and teleoperation are often presented as alternatives they are obviously symbiotic. The natural model for reasonably advanced machines is one in which local issues such as orientation, obstacle avoidance, and manipulator control are handled locally, autonomously, while humans feed the machine directions on high-level matters such as targets, output specs, and rates. While at present this model is usually found only in machines built to work in dangerous environments, it is easy to imagine it in a wide range of contexts, including agriculture, construction, transportation, mining, and manufacturing, not to mention a host of research applications. Of course nanotechnology is entirely inconceivable without a comprehensive development of this model. It is worth noting that the humans issuing these more general directions are likely to be physically separate from the machines themselves, for reasons that include safety, economy (accommodating human operators inside or on the machine itself adds expense and often degrades function), and efficiency: local autonomy permits operators to run large numbers of machines in many locations simultanously. One implication of remote operation is how it defines the path of sensor and AI development: once the market becomes familiar with the core idea it will be simple to pitch successive generations of products, each promising incremental increases in the number of machines that can be controlled by a single human during a specific productive cycle. Perhaps there is a Moore's law type curve in here somewhere. There are also intriguing cultural implications. Many cultural roles depend on a close physical association with machines. There are many examples -- truckers wrestling with their rigs, pilots, skippers -- but the most extreme example is the connection we have with our guns. Police work might be very different, both in how it feels as a job and in its cultural resonance, if guns were controlled by patrolmen in an armored car telling a fleet of microhornets to return fire, or by guys sitting in cubicles downtown clicking on spots on a screen. Local autonomy also destroys the exclusivity of access to complicated machines, both by lowering operating skill requirements and by opening up the possibilities of remote audiences. Finally, local autonomy and remote operation make it unnecessary for anyone to expose themselves to dangerous situations of any kind. Once this fact is internalized, movie makers interested in showing heroes going into danger will be forced to rely on historical (or perhaps alternate universe) dramas, since most audiences watching a contemporary hero take chances will wonder why he didn't do what anyone else would have: send a machine in instead. Past business: William Ware reports the discovery of a web page summarizing George Whitesides' talk on soft lithography: http://itri.loyola.edu/nano/us_r_n_d/04_02.htm Nanonews: Microlab slashes cost of DNA testing. http://www.umich.edu/~newsinfo/Releases/1998/Oct98/r102198b.html Rice University and NASA officials form nanotube research consortium. http://www.eurekalert.org/releases/ru-nmdnff.html cybernetic materials http://www.eurekalert.org/releases/im-sms.html enzyme engineering http://www.eurekalert.org/releases/ciw_cdpe.html neural materials (resonant tunneling diodes) http://www.eurekalert.org/releases/ns-sssco.html Recombinant biochem Adapted from the release: A current method of making new proteins is to use ultraviolet light or a DNA-disrupting chemical to make genes mutate and make proteins from the mutations. Typically only 1 in a hundred mutations made this way is interesting. By comparison, in the reported test 13 per cent of the enzymes produced through "DNA shuffling" were superior to the original. The best, a version of interferon, was 285,000 times as potent. http://www.eurekalert.org/releases/ns-wgbitl.html Smallest possible bipolar transistor is built. http://www.eurekalert.org/releases/weiz-hmcwg.html Announcement Archive: http://world.std.com/~fhapgood/nsgpage.html. Comments to: hapgood@pobox.com