Meeting notice: The 05-18-99 meeting will be held at 7:30 p.m. at the Royal East (782 Main St., Cambridge), a block down from the corner of Main St. and Mass Ave. If you're new and can't recognize us, ask the manager. He'll probably know where we are. Suggested topic: The practice of synthetic chemistry, and particularly biochemistry, has always imposed high entry costs of talent and education. As we move towards finer and firmer control of the molecular domain, those costs should fall. At some point, perhaps halfway between now and the onset of NT (10 years?, 15?), people no more talented or knowledgeable than the average programmer (say) should be able to perform chemical and biochemical operations in their home (or remotely, in a net-accessible lab) that would be quite out of reach for them today. The effect would be to create a population of biochem experimenters, hobbyists, and casual gene hackers that is ten to a hundred times larger than the present day biochem community. The current pace of biotech is a function of the number of those working in it and the inhibitions imposed by regulatory structures and organizational oversight. (Imagine the pace of software development if every new piece of code had to be examined, tested, and approved by an FDA-like Federal Software Agency.) A 10 or 20 or 30 fold increase in the number of researchers over the globe as a whole would probably destroy this system, accelerating development by more than a linear increase in the number of workers. The consequences of this acceleration may merit our interest. The production of poisons, explosives, pharmaceuticals, and recreational substances would fall definitively into the hands of end-users. Cosmetics might in time come to adopt a gene model: naturally red lips, naturally secreted perfumes, etc. Gardeners, hobbyists, farmers, and breeders of plants and animals would start experimenting aggressively with a wide range of gene transfers. It seems impossible to doubt that some of these experiments would escape to the wild; eventually a great many of them would. The time might come when most of the plants and animals we see around us will be artificial in this sense. Politics would of course be affected: activists would not need to demonstrate against (for instance) Monsanto's new line of terminator seeds; they would just fix the genes directly or, even better, write a library of terminatorless seed genomes and then put them all under 'copyleft', threatening the company's business model. Finally, yet another form of intellectual property would become worthless, though in this case the size of the sectors involved -- chemicals, pharmaceuticals -- suggests that the inevitable industry temper tantrum might clock in at an F-4, or even an F-5. <><><><><><><><><><><><><><><><><><><><><><><><><><><><> MEMS rolls on Dept: Allen Majorovic recently posted the following interesting URL to sci.nanotech: http://www.isi.edu/efab/ <><><><><><><><><><><><><><><><><><><><><><><><><><><><> Announcement Archive: http://world.std.com/~fhapgood/nsgpage.html. <><><><><><><><><><><><><><><><><><><><><><><><><><><><> Comments to: hapgood@pobox.com